Unveiling molecular mechanisms of viral infection
Using molecular and cell biological methods, we have been analyzing virus-host interactions during Arboviruses, Rabies virus infection. Our research aims at Conducting epidemiological surveys in Zambia in order to study the life cycles of various viruses. Understanding the molecular mechanisms of viral pathogenicity and developing techniques for prevention and treatment of neurotropic viral infections based on facts obtained.
- Hirofumi SAWA
- Yasuko ORBA
- Specially Appointed Assistant Professor
- Michihito SASAKI
Wada Y, Orba Y, Sasaki M, Kobayashi S, Carr MJ, Nobori H, Sato A, Hall WW, Sawa H. Discovery of a novel antiviral agent targeting the nonstructural protein 4 (nsP4) of chikungunya virus. Virology. 505:102-112.2017
Phongphaew W, Kobayashi S, Sasaki M, Carr M, Hall WW, Orba Y, Sawa H. Valosin-containing protein (VCP/p97) plays a role in the replication of West Nile virus. Virus Res.15;228:114-123.2017
Sasaki M, Gonzalez G, Wada Y, Setiyono A, Handharyani E, Rahmadani I, Taha S, Adiani S, Latief M, Kholilullah ZA, Subangkit M, Kobayashi S, Nakamura I, Kimura T, Orba Y, Ito K, Sawa H.
Divergent bufavirus harboured in megabats represents a new lineage of parvoviruses. Sci Rep. 26;6:24257. 2016