発表論文

2024

  1. Sasaki M, Sugi T, Iida S, Hirata Y, Kusakabe S, Konishi K, Itakura Y, Tabata K, Kishimoto M, Kobayashi H, Ariizumi T, Intaruck K, Nobori H, Toba S, Sato A, Matsuno K, Yamagishi J, Suzuki T, Hall WW, Orba Y, Sawa H. Combination therapy with oral antiviral and anti-inflammatory drugs improves the efficacy of delayed treatment in a COVID-19 hamster model. EBioMedicine. 2024 Jan;99:104950.
  2. Handabile C, Ohno M, Sekiya T, Nomura N, Kawakita T, Kawahara M, Endo M, Nishimura T, Okumura M, Toba S, Sasaki M, Orba Y, Chua BY, Rowntree LC, Nguyen THO, Shingai M, Sato A, Sawa H, Ogasawara K, Kedzierska K, Kida H. Immunogenicity and protective efficacy of a co-formulated two-in-one inactivated whole virus particle COVID-19/influenza vaccine. Sci Rep. 2024 Feb 20;14(1):4204.
  3. Tsumita T, Takeda R, Maishi N, Hida Y, Sasaki M, Orba Y, Sato A, Toba S, Ito W, Teshirogi T, Sakurai Y, Iba T, Naito H, Ando H, Watanabe H, Mizuno A, Nakanishi T, Matsuda A, Zixiao R, Lee JW, Iimura T, Sawa H, Hida K. Viral uptake and pathophysiology of the lung endothelial cells in age-associated severe SARS-CoV-2 infection models. Aging Cell. 2024 Feb;23(2):e14050.
  4. Ariizumi T, Tabata K, Itakura Y, Kobayashi H, Hall WW, Sasaki M, Sawa H, Matsuno K, Orba Y. Establishment of a lethal mouse model of emerging tick-borne orthonairovirus infections. PLoS Pathog. 2024 Mar 19;20(3):e1012101.
  5. Hiono T, Sakaue H, Tomioka A, Kaji H, Sasaki M, Orba Y, Sawa H, Kuno A. Combinatorial Approach with Mass Spectrometry and Lectin Microarray Dissected Site-Specific Glycostem and Glycoleaf Features of the Virion-Derived Spike Protein of Ancestral and γ Variant SARS-CoV-2 Strains. J Proteome Res. 2024 Apr 5;23(4):1408-1419.

2023

  1. Orba Y, Abu YE, Chambaro HM, Lundu T, Muleya W, Eshita Y, Qiu Y, Harima H, Kajihara M, Mori-Kajihara A, Matsuno K, Sasaki M, Hall WW, Hang’ombe BM, Sawa H. Expanding diversity of bunyaviruses identified in mosquitoes. Sci Rep. 2023 Oct 24;13(1):18165.
  2. Uemura K, Nobori H, Sato A, Toba S, Kusakabe S, Sasaki M, Tabata K, Matsuno K, Maeda N, Ito S, Tanaka M, Anraku Y, Kita S, Ishii M, Kanamitsu K, Orba Y, Matsuura Y, Hall WW, Sawa H, Kida H, Matsuda A, Maenaka K. 2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses. Proc Natl Acad Sci U S A. 2023 Oct 17;120(42):e2304139120.
  3. Tabata K, Itakura Y, Ariizumi T, Igarashi M, Kobayashi H, Intaruck K, Kishimoto M, Kobayashi S, Hall WW, Sasaki M, Sawa H, Orba Y. Development of flavivirus subviral particles with low cross-reactivity by mutations of a distinct antigenic domain. Appl Microbiol Biotechnol. 2023 Dec;107(24):7515-7529.
  4. Kobayashi S, Kawakami R, Takeda C, Maezono K, Thammahakin P, Eguchi H, Hang’ombe BM, Orba Y, Sawa H, Yoshii K, Kariwa H. Ubiquitin accumulation induced by the finger and palm sub-domains of NS5 modulates the replication of West Nile virus. Virology. 2023 Nov;588:109902.
  5. Ndebe J, Harima H, Chambaro HM, Sasaki M, Yamagishi J, Kalonda A, Shawa M, Qiu Y, Kajihara M, Takada A, Sawa H, Saasa N, Simulundu E. Prevalence and Genomic Characterization of Rotavirus A from Domestic Pigs in Zambia: Evidence for Possible Porcine-Human Interspecies Transmission.Pathogens. 2023 Sep 27;12(10):1199.
  6. Velu RM, Kwenda G, Bosomprah S, Chisola MN, Simunyandi M, Chisenga CC, Bumbangi FN, Sande NC, Simubali L, Mburu MM, Tembo J, Bates M, Simuunza MC, Chilengi R, Orba Y, Sawa H, Simulundu E. Ecological Niche Modeling of Aedes and CulexMosquitoes: A Risk Map for Chikungunya and West Nile Viruses in Zambia. Viruses. 2023 Sep 8;15(9):1900.
  7. Izumi F, Miyamoto S, Masatani T, Sasaki M, Kawakami K, Takahashi T, Fujiwara T, Fujii Y, Okajima M, Nishiyama S, Sawa H, Sugiyama M, Ito N. Generation and characterization of a genetically modified live rabies vaccine strain with attenuating mutations in multiple viral proteins and evaluation of its potency in dogs. Vaccine. 2023 Jul 25;41(33):4907-4917.
  8. Harima H, Qiu Y, Yamagishi J, Kajihara M, Changula K, Okuya K, Isono M, Yamaguchi T, Ogawa H, Nao N, Sasaki M, Simulundu E, Mweene AS, Sawa H, Ishihara K, Hang’ombe BM, Takada A. Surveillance, Isolation, and Genetic Characterization of Bat Herpesviruses in Zambia. Viruses. 2023 Jun 13;15(6):1369.
  9. Itakura Y, Tabata K, Saito T, Intaruck K, Kawaguchi N, Kishimoto M, Torii S, Kobayashi S, Ito N, Harada M, Inoue S, Maeda K, Takada A, Hall WW, Orba Y, Sawa H, Sasaki M. Morphogenesis of Bullet-Shaped Rabies Virus Particles Regulated by TSG101. J Virol. 2023 May 31;97(5):e0043823.
  10. Taoda Y, Sato A, Toba S, Unoh Y, Kawai M, Sasaki M, Orba Y, Sawa H. Structure-activity relationship studies of anti-bunyaviral cap-dependent endonuclease inhibitors. Bioorg Med Chem Lett. 2023 Mar 1;83:129175.
  11. Sasaki M, Tabata K, Kishimoto M, Itakura Y, Kobayashi H, Ariizumi T, Uemura K, Toba S, Kusakabe S, Maruyama Y, Iida S, Nakajima N, Suzuki T, Yoshida S, Nobori H, Sanaki T, Kato T, Shishido T, Hall WW, Orba Y, Sato A, Sawa H. S-217622, a SARS-CoV-2 main protease inhibitor, decreases viral load and ameliorates COVID-19 severity in hamsters. Sci Transl Med. 2023 Jan 18;15(679):eabq4064.
  12. Kishimoto M, Kajihara M, Tabata K, Itakura Y, Toba S, Ozono S, Sato Y, Suzuki T, Ito N, Changula K, Qiu Y, Mori-Kajihara A, Eto Y, Harima H, Mwizabi D, Hang’ombe BM, Hall WW, Takada A, Orba Y, Sawa H, Sasaki M. Isolation and Characterization of Distinct Rotavirus A in Bat and Rodent Hosts. J Virol. 2023 Jan 31;97(1):e0145522.
  13. Kainga H, Chatanga E, Phonera MC, Kothowa JP, Dzimbiri P, Kamwendo G, Mulavu M, Khumalo CS, Changula K, Chambaro H, Harima H, Kajihara M, Mkandawire K, Chikungwa P, Chulu J, Njunga G, Chitanga S, Mubemba B, Sasaki M, Orba Y, Qiu Y, Yamagishi J, Simulundu E, Takada A, Namangala B, Sawa H, Muleya W*. Current status and molecular epidemiology of rabies virus from different hosts and regions in Malawi. Arch Virol. 2023 Jan 12;168(2):61.
  14. Qiu Y, Chambaro HM, Sato K, Squarre D, Simulundu E, Kajihara M, Changula K, Simbotwe M, Harima H, Ndebe J, Moonga L, Nakao R, Takada A, Hang’ombe BM, Sawa H, Kawabata H. Detection of Old and New World Relapsing Fever Borreliae in Ornithodoros Ticks Collected from Warthog Burrows in Zambia. Microorganisms. 2023 Jan 12;11(1):200.

2022

  1. Rini EP, Sasaki M, Astuti D, Juniantito V, Wibawan IWT, Sawa H, Setiyono A. First molecular detection of Coxiella burnetii in beef cattle in West Java, Indonesia. Jpn J Infect Dis, Jan 24;75(1):83-85. 2022
  2. Hasegawa T, Imamura Rm, Suzuki T, Hashiguchi T, Nomura T, Otsuguro S, Maenaka K, Sasaki M, Orba Y, Sawa H, Sato A, Okabe T, Nagano T, Kojima H: Application of acoustic ejection MS system to high-throughput screening for SARS-CoV-2 3CL protease inhibitors. Chem Pharm Bull Mar 1;70(3):199-201, 2022
  3. Squarre D, Chambaro HM, Hayashida K, Moonga LC, Qiu Y, Goto Y, Oparaocha E, Mumba C, Muleya W, Bwalya P, Chizimu J, Chembensofu M, Simulundu E, Mwasinga W, Banda N, Mwenda R, Yamagishi J, Nalubamba KS, Banda F, Munyeme M, Sawa H, Fandamu P: Autochthonous Leishmania infantum in dogs, Zambia, 2021          Emerg Infect Dis Apr;28(4):888-890, 2022
  4. Mubemba B, Mburu M, Changula K, Muleya W, Moonga LC, Chambaro HM, Kajihara M, Qiu Y, Orba Y, Hayashida K, Sutcliffe CG, Norris DE, Thuma PE, Ndubani P, Chitanga S, Sawa H, Takada A, Simulundu E: Current knowledge of vector-borne zoonotic pathogens in Zambia: A clarion call to scaling-up “One Health” research in the wake of emerging and re-emerging infectious diseases. PLoS Negl Trop Dis Feb 4;16(2):e0010193, 2022
  5. Suzuki R, Yamasoba D, Kimura I, Wang L, Kishimoto M, Ito J, Morioka Y, Nao N, Nasser H, Uriu K, Kosugi Y, Tsuda M, Orba Y, Sasaki M, Shimizu R, Kawabata R, Yoshimatsu K, Asakura H, Nagashima M, Sadamasu K, Yoshimura K, The Genotype to Phenotype Japan (G2P-Japan) Consortium, Sawa H, Ikeda T, Irie T, Matsuno K, Tanaka S, Fukuhara T, Sato K. Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant. Nature Mar;603(7902):700-705, 2022
  6. Nakamura M, Uemura K, Saito-Tarashima N, Sato A, Orba Y, Sawa H, Matsuda A, Maenaka K, Minakawa N. Synthesis and anti-dengue virus activity of 5-ethynylimidazole-4-carboxamide (EICA) nucleotide prodrugs. Chem Pharm Bull. Mar 1;70(3):220-225, 2022
  7. Itakura Y, Tabata K, Morimoto K, Ito N, Chambaro HM, Eguchi R, Otsuguro-Ki, Hall WW, Orba Y, Sawa H, Sasaki M. Glu333 in rabies virus glycoprotein is involved in virus attenuation through astrocyte infection and interferon responses. iScience Mar 22;25(4):104122, 2022
  8. Okuya K, Hattori T, Saito T, Takadate Y, Sasaki M, Furuyama W, Marzi A, Ohiro Y, Konno S, Hattori T, Takada A. Multiple Routes of Antibody-Dependent Enhancement of SARS-CoV-2 Infection. Microbiol Spectr. Apr 27;10(2):e0155321, 2022
  9. Squarre D, Chambaro HM, Hayashida K, Moonga LC, Qiu Y, Goto Y, Oparaocha E, Mumba C, Muleya W, Bwalya P, Chizimu J, Chembensofu M, Simulundu E, Mwasinga W, Banda N, Mwenda R, Yamagishi J, Nalubamba KS, Banda F, Munyeme M, Sawa H, Fandamu P. Autochthonous Leishmania infantum in Dogs, Zambia, 2021. Emerg Infect Dis. 2022 Apr;28(4):888-890.
  10. Harima H, Okuya K, Kajihara M, Ogawa H, Simulundu E, Bwalya E, Qiu Y, Mori-Kajihara A, Munyeme M, Sakoda Y, Saito T, Hang’ombe BM, Sawa H, Mweene AS, Takada A. Serological and molecular epidemiological study on swine influenza in Zambia. Transbound Emerg Dis. 2022 Jul;69(4):e931-e943.
  11. Yamasoba D, Kimura I, Nasser H, Morioka Y, Nao N, Ito J, Uriu K, Tsuda M, Zahradnik J, Shirakawa K, Suzuki R, Kishimoto M, Kosugi Y, Kobiyama K, Hara T, Toyoda M, Tanaka YL, Butlertanaka EP, Shimizu R, Ito H, Wang L, Oda Y, Orba Y, Sasaki M, Nagata K, Yoshimatsu K, Asakura H, Nagashima M, Sadamasu K, Yoshimura K, Kuramochi J, Seki M, Fujiki R, Kaneda A, Shimada T, Nakada TA, Sakao S, Suzuki T, Ueno T, Takaori-Kondo A, Ishii KJ, Schreiber G; Genotype to Phenotype Japan (G2P-Japan) Consortium; Sawa H, Saito A, Irie T, Tanaka S, Matsuno K, Fukuhara T, Ikeda T, Sato K. Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike. Cell. 2022 Jun 9;185(12):2103-2115.e19.
  12. Qiu Y, Simuunza M, Kajihara M, Ndebe J, Saasa N, Kapila P, Furumoto H, Lau ACC, Nakao R, Takada A, Sawa H. Detection of Tick-Borne Bacterial and Protozoan Pathogens in Ticks from the Zambia-Angola Border. Pathogens. 2022 May 10;11(5):566.
  13. Unoh Y, Uehara S, Nakahara K, Nobori H, Yamatsu Y, Yamamoto S, Maruyama Y, Taoda Y, Kasamatsu K, Suto T, Kouki K, Nakahashi A, Kawashima S, Sanaki T, Toba S, Uemura K, Mizutare T, Ando S, Sasaki M, Orba Y, Sawa H, Sato A, Sato T, Kato T, Tachibana Y. Discovery of S-217622, a Noncovalent Oral SARS-CoV-2 3CL Protease Inhibitor Clinical Candidate for Treating COVID-19. J Med Chem. 2022 May 12;65(9):6499-6512.
  14. Minagawa H, Sawa H, Fujita T, Kato S, Inaguma A, Hirose M, Orba Y, Sasaki M, Tabata K, Nomura N, Shingai M, Suzuki Y, Horii K. A high-affinity aptamer with base-appended base-modified DNA bound to isolated authentic SARS-CoV-2 strains wild-type and B.1.617.2 (delta variant). Biochem Biophys Res Commun. 2022 Jul 23;614:207-212.
  15. Chambaro HM, Hirose K, Sasaki M, Libanda B, Sinkala Y, Fandamu P, Muleya W, Banda F, Chizimu J, Squarre D, Shawa M, Qiu Y, Harima H, Eshita Y, Simulundu E, Sawa H, Orba Y. An unusually long Rift valley fever inter-epizootic period in Zambia: Evidence for enzootic virus circulation and risk for disease outbreak. PLoS Negl Trop Dis. 2022 Jun 2;16(6):e0010420.
  16. Tabata K, Itakura Y, Toba S, Uemura K, Kishimoto M, Sasaki M, Harrison JJ, Sato A, Hall WW, Hall RA, Sawa H, Orba Y. Serological characterization of lineage II insect-specific flaviviruses compared with pathogenic mosquito-borne flaviviruses. Biochem Biophys Res Commun. 2022 Aug 6;616:115-121.
  17. Takeda R, Sawa H, Sasaki M, Orba Y, Maishi N, Tsumita T, Ushijima N, Hida Y, Sano H, Kitagawa Y, Hida K. Antiviral effect of cetylpyridinium chloride in mouthwash on SARS-CoV-2. Sci Rep. 2022 Aug 18;12(1):14050.
  18. Katowa B, Kalonda A, Mubemba B, Matoba J, Shempela DM, Sikalima J, Kabungo B, Changula K, Chitanga S, Kasonde M, Kapona O, Kapata N, Musonda K, Monze M, Tembo J, Bates M, Zumla A, Sutcliffe CG, Kajihara M, Yamagishi J, Takada A, Sawa H, Chilengi R, Mukonka V, Muleya W, Simulundu E. Genomic Surveillance of SARS-CoV-2 in the Southern Province of Zambia: Detection and Characterization of Alpha, Beta, Delta, and Omicron Variants of Concern. Viruses. 2022 Aug 24;14(9):1865.
  19. Toba S, Sato A, Kawai M, Taoda Y, Unoh Y, Kusakabe S, Nobori H, Uehara S, Uemura K, Taniguchi K, Kobayashi M, Noshi T, Yoshida R, Naito A, Shishido T, Maruyama J, Paessler S, Carr MJ, Hall WW, Yoshimatsu K, Arikawa J, Matsuno K, Sakoda Y, Sasaki M, Orba Y, Sawa H, Kida H. Identification of cap-dependent endonuclease inhibitors with broad-spectrum activity against bunyaviruses. Proc Natl Acad Sci U S A. 2022 Sep 6;119(36):e2206104119.
  20. Hirose H, Hirai Y, Sasaki M, Sawa H, Futaki S. Quantitative Analysis of Extracellular Vesicle Uptake and Fusion with Recipient Cells. Bioconjug Chem. 2022 Oct 19;33(10):1852-1859.
  21. Hirose Y, Shindo N, Mori M, Onitsuka S, Isogai H, Hamada R, Hiramoto T, Ochi J, Takahashi D, Ueda T, Caaveiro JMM, Yoshida Y, Ohdo S, Matsunaga N, Toba S, Sasaki M, Orba Y, Sawa H, Sato A, Kawanishi E, Ojida A. Discovery of Chlorofluoroacetamide-Based Covalent Inhibitors for Severe Acute Respiratory Syndrome Coronavirus 2 3CL Protease. J Med Chem. 2022 Oct 27;65(20):13852-13865.
  22. Intaruck K, Itakura Y, Kishimoto M, Chambaro HM, Setiyono A, Handharyani E, Uemura K, Harima H, Taniguchi S, Saijo M, Kimura T, Orba Y, Sawa H, Sasaki M. Isolation and characterization of an orthoreovirus from Indonesian fruit bats. Virology. 2022 Oct;575:10-19.
  23. Shimizu H, Kodama M, Matsumoto M, Orba Y, Sasaki M, Sato A, Sawa H, Nakayama KI. LIGHTHOUSE illuminates therapeutics for a variety of diseases including COVID-19. iScience. 2022 Oct 10;25(11):105314.
  24. Saito A, Tamura T, Zahradnik J, Deguchi S, Tabata K, Anraku Y, Kimura I, Ito J, Yamasoba D, Nasser H, Toyoda M, Nagata K, Uriu K, Kosugi Y, Fujita S, Shofa M, Monira Begum M, Shimizu R, Oda Y, Suzuki R, Ito H, Nao N, Wang L, Tsuda M, Yoshimatsu K, Kuramochi J, Kita S, Sasaki-Tabata K, Fukuhara H, Maenaka K, Yamamoto Y, Nagamoto T, Asakura H, Nagashima M, Sadamasu K, Yoshimura K, Ueno T, Schreiber G, Takaori-Kondo A; Genotype to Phenotype Japan (G2P-Japan) Consortium; Shirakawa K, Sawa H, Irie T, Hashiguchi T, Takayama K, Matsuno K, Tanaka S, Ikeda T, Fukuhara T, Sato K. Virological characteristics of the SARS-CoV-2 Omicron BA.2.75 variant. Cell Host Microbe. 2022 Nov 9;30(11):1540-1555.e15.
  25. Saito S, Funayama K, Kato W, Okuda M, Kawamoto M, Matsubara T, Sato T, Sato A, Otsuguro S, Sasaki M, Orba Y, Sawa H, Maenaka K, Shindo K, Imoto M, Arai MA. Dihydromaniwamycin E, a Heat-Shock Metabolite from Thermotolerant Streptomyces sp. JA74, Exhibiting Antiviral Activity against Influenza and SARS-CoV-2 Viruses. J Nat Prod. 2022 Nov 25;85(11):2583-2591.
  26. Munjita SM, Moonga G, Mukubesa AN, Ndebe J, Mubemba B, Vanaerschot M, Tato C, Tembo J, Kapata N, Chitanga S, Changula K, Kajihara M, Muleya W, Takada A, Fichet-Calvet E, Zumla A, Sawa H, Bates M, Munsaka S, Simulundu E. Luna Virus and Helminths in Wild Mastomys natalensis in Two Contrasting Habitats in Zambia: Risk Factors and Evidence of Virus Dissemination in Semen. Pathogens. 2022 Nov 14;11(11):1345.
  27. Kainga H, Phonera MC, Chatanga E, Kallu SA, Mpundu P, Samutela M, Chambaro HM, Kajihara M, Shempela DM, Sikalima J, Muleya W, Shawa M, Chulu J, Njunga G, Simuunza M, Takada A, Sawa H, Simulundu E, Saasa N. Seroprevalence and Associated Risk Factors of Rift Valley Fever in Livestock from Three Ecological Zones of Malawi. Pathogens. 2022 Nov 14;11(11):1349.

2021

  1. Sasaki M, Uemura K, sato A, Toba S, Sanaki T, Maenaka K, Hall WW, Orba Y,  Sawa H: SARS-CoV-2 variants with mutations at the S1/S2 cleavage site are generated in vitro during propagation in TMPRSS2-deficient cells. PLoS Pathog Jan 21; 17(1): e1009233, 2021
  2. Mwenda M, Saasa N, Sinyange N, Busby G, Chipimo PJ, Hendry J, Kapona O, Yingst S, Hines JZ, Minchella P, Simulundu E, Changula K, Nalubamba KS, Sawa H, Kajihara M, Yamagishi J, Kapin’a M, Kapata N, Fwoloshi S, Zulu P, Mulenga LB, Agolory S, Mukonka V, Bridges DJ: Detection of B.1.351 SARS-CoV-2 Variant Strain — Zambia, December 2020. MMWR Morb Mortal Wkly Rep February 26, 70(8);280–282, 2021
  3. Simulundu E, Mbambara S, Chambaro MH, Sichibalo K, Kajihara M, Sawa H, Takada A, Changula K, Chitanga S: Prevalence and genetic diversity of Shibuyunji virus, a novel tick-borne phlebovirus identified in Zambia. Arch Virol Mar;166(3):915-919, 2021
  4. Kishimoto M, Hang’ombe BM, Hall WW, Orba Y, Sawa H, Sasaki: Mastomys natalensis is a possible natural rodent reservoir for encephalomyocarditis virus. J Gen Virol Mar;102(3), 2021
  5. Harima H, Orba Y, Torii S, Qiu Y, Kajihara M, Eto Y, Matsuta N, Hang’ombe BM, Eshita Y, Uemura K, Matsuno K, Sasaki M, Yoshii K, Nakao R, Hall WW, Takada A, Abe T, Wolfinger MT, Simuunza M Sawa H*: An African tick flavivirus forming an independent clade exhibits unique exoribonuclease-resistant RNA structures in the genomic 3’-untranslated region. Sci Rep Mar 1;11(1):4883, 2021. (*corresponding author)
  6. Uemura K, Sasaki M, Sanaki T, Toba S, Takahsshi Y, Orba Y, Hall WW, Maenaka K, Sawa H, Sato A: MRC5 cells engineered to express angiotensin-converting enzyme 2 serve as a useful model system for the discovery and screening of antivirals targeting SARS-CoV-2. Sci Rep Mar 8;11(1):5376, 2021
  7. Kishimoto M, Uemura K, Sanaki T, Sato A, Hall WW, Kariwa H, Orba Y, Sawa H, Sasaki M: TMPRSS11D and TMPRSS13 activate the SARS-CoV-2 spike protein. Viruses Feb 28;13(3):384, 2021
  8. Sasaki M, Itakura Y, Kishimoto M, Tabata K, Uemura K, Ito N, Sugiyama M, Wastika CE, Orba Y, Sawa H: Host serine proteases TMPRSS2 and TMPRSS11D mediate proteolytic activation and trypsin-independent infection in group A rotaviruses. J Virol Mar 24;95(11):e00398-21, 2021
  9. Qiu Y, Simuunza M, Kajihara M, Chambaro H, Harima H, Eto Y, Simulundu E, Squarre D, Torii S, Takada A, Hang’ombe BM, Sawa H, Sugimoto C, Nakao R: Screening of tick-borne pathogens in argasid ticks in Zambia: Expansion of the geographic distribution of Rickettsia lusitaniae and Rickettsia hoogstraalii and detection of putative novel Anaplasma species. Ticks Tick Borne Dis Apr 5;12(4):101720, 2021
  10. Squarre D, Chizimu J, Nakajima C, Muma JB, Hang’ombe BM, Simulundu E, Mwasinga W, Katampi J, Fandamu P, Mukonka V, Suzuki Y, Sawa H, Munang’andu HM, Shanungu G, Chambaro HM, Munyeme M. First report of Mycobacterium bovis in wild chacma baboons (Papio ursinus) at the human-wildlife interface area in Zambia.
    Transbound Emerg Dis. Apr 26, 2021
  11. Kaneko C, Omori R, Sasaki M, Kataoka-Nakamura C, Simulundu E, Muleya W, Moonga L, Ndebe J, Hang’ombe BM, Dautu G, Qiu Y, Nakao R, Kajihara M, Mori-Kajihara A, Chambaro HM, Higashi H, Sugimoto C, Sawa H, Mweene AS, Takada A, Isoda N. Domestic dog demographics and estimates of canine vaccination coverage in a rural area of Zambia for the elimination of rabies. PLoS Negl Trop Dis Apr 28;15(4):e0009222, 2021
  12. Kajihara M, Simuunza M, Saasa N, Dautu G, Mori-Kajihara A, Qiu Y, Furumoto H, Hang’ombe BM, Orba Y, Sawa H, Simulundu E, Fukushi S, Morikawa S, Saijo M, Arikawa J, Kabilika S, Monze M, Mukonka V, Mweene A, Yoshimatsu K, Takada A. Serologic and molecular evidence for circulation of Crimean-Congo hemorrhagic fever virus in ticks and cattle in Zambia.  PLoS Neglect Trop Dis Jun 1;15(6):e0009452, 2021
  13. Yamada T, Saito S, Sotoyama Y, Orba Y, Sawa H, Yamauchi H, Sasaki M, Takaoka A. RIG-I triggers a signaling-abortive anti-SARSCoV-2 defense in human lung cells.   Nat Immunol Jul;22(7):820-828, 2021
  14. Nakamura K, Fujiki J, Furusawa T, Nakamura T, Gondaira S, Sasaki M, Usui M, Higuchi H, Sawa H, Tamura Y, Iwano H. Complete genome sequence of /Pseudomonas aeruginosa/ veterinary isolate, Pa12.  Microbiol Resour Announc  Jul;10(26):e0039821, 2021
  15. Ito N, Okamoto T, Sasaki M, Miyamoto S, Takahashi T, Izumi F, Inukai M, Jarusombuti S, Okada K, Nakagawa K, Fujii Y, Nishiyama S, Masatani T, Sawa H, Sugiyama M. Safety enhancement of a genetically modified live rabies vaccine strain by introducing an attenuating Leu residue at position 333 in the glycoprotein. Vaccine 23;39(28):3777-3784, 2021
  16. Kaneko C, Sasaki M, Omori R, Nakao R, Kataoka-Nakamura C, Moonga L, Ndebe J, Muleya W, Simulundu E, Hang’ombe BM, Dautu G, Kajihara M, Mori-Kajihara A, Qiu Y, Ito N, Chambaro HM, Sugimoto C, Higashi H, Takada A, Sawa H, Mweene AS, Isoda N. Immunization coverage and antibody retention against rabies in domestic dogs in Lusaka district, Zambia. Pathogens Jun 11;10(6):738, 2021
  17. Kobayashi T, Chatanga E, Qiu Y, Simuunza M, Kajihara M, Hang’ombe BM, Eto Y, Saasa N, Mori-Kajihara A, Simulundu E, Takada A, Sawa H, Katakura K, Nonaka N, Nakao R*. Molecular detection and genotyping of Coxiella-like endosymbionts in ticks collected from animals and vegetation in Zambia. Pathogens 10, 779 , 2021 
  18. Changula K, Simulundu E, Lombe BP, Nakayama E, Miyamoto H, Takahashi Y, Sawa H, Simukonda S, Hang’ombe BM, Takada A: Serological evidence of filovirus infection in nonhuman primates in Zambia. Viruses Jun 30;13(7):1283, 2021
  19. Velu RM, Kwenda G, Libonda L, Chisenga CC, Flavien BN, Chilyabanyama ON, Simunyandi M, Bosomprah S, Sande NC, Changla K, Muleya W, Mburu MM, Mubemba M, Chitanga S, Tembo J, Bates M, Kapata N, Orba Y, Kajihara M, Takada A, Sawa H*, Chilengi R, Simulundu E: Mosquito-borne viral pathogens detected in Zambia: A systematic review. Pathogens Aug 10;10(8):1007, 2021.
  20. Fujiki J, Yoshida S-i, Nakamura T, Nakamura K, Amano Y, Nishida K, Nishi K, Sasaki M, Iwasaki T, Sawa H, Komatsuzawa H, Hijioka H, Iwano H: Novel virulent bacteriophage ØSG005 against Streptococcus gordonii forming a distinct clade in Streptococcus viruses. Viruses Sep 29;13(10):1964, 2021.
  21. Uemura K, Nobori H, Sato A, Sanaki T, Toba S, Sasaki M, Murai A, Saito-Tashima N, Minakawa N, Orba Y, Kariwa H, Hall WW, Sawa H, Matsuda A, Maenaka K: 5-Hydroxymethyltubercidin exhibits potent antiviral activity against Flaviviruses and Coronaviruses, including SARS-CoV-2. iScience Sep 11:103120. 2021
  22. Harima H, Sasaki M, Orba Y, Okuya K, Qiu Y, Wastika CE, Changula K, Kajihara M, Simulundu E, Yamaguchi T, Eto Y, Mori-Kajihara A, Sato A, Taniguchi S, Takada A, Saijo M, Hang’ombe BM, Sawa H: Attenuated infection by a Pteropine Bay orthoreovirus isolated from an Egyptian fruit bat in Zambia. PLoS Negl Trop Dis Sep 7;15(9):e0009768, 2021
  23. Reteng B, Thuy LN, Minh TTT, Mares-Guia MAMM, Torres MC, Filippis AMB, Orba Y, Kobayashi S, Hayashida K, Sawa H, Hall WW, Thi LAN, Yamagishi J: Targeted approach with nanopore sequencing for the universal detection and identification of flaviviruses. Sci Rep Sep 24;11(1):19031, 2021
  24. Sasaki M, Toba S, Itakura Y, Chambaro HM, Kishimoto M, Tabata K, Intaruck K, Uemura K, Sanaki T, Sato A, Hall WW, Orba Y, Sawa H: SARS-CoV-2 bearing a mutation at the S1/S2 cleavage site exhibits attenuated virulence and confers protective immunity. mBio Aug 24;e0141521, 2021
  25. Ogata S, Pereira JAC, Jhonny LVA, Carolina HPG, Matsuno K, Orba Y, Sawa H, Kawamori F, Nonaka N, Nakao R: Molecular survey of Babesia and Anaplasma infection in cattle in Bolivia. Vet Sci Sep 7;8(9):188. doi: 10.3390/vetsci8090188.
  26. Kodama F, Yamaguchi H, Park E, Tatemoto K, Sashika M, Nakao R, Terauchi Y, Mizuma K, Orba Y, Kariwa H, Hagiwara K, Ozaki K, Goto A, Komagome R, Miyoshi M, Ito T, Yamano K, Yoshii K, Funaki C, Ishiduka M, Dhigeno A, Itakura Y, Bell-Sakyl L, Edgawa S, Nagasaka A, Sakoda Y, Sawa H, Maeda K, Saijo M, Matsuno K: A novel nairovirus associated with acute febrile illness in Hokkaido, Japan. Nat Commun Sep 20;12(1):5539, 2021
  27. Onodera T, Kita S, Adachi Y, Moriyama S, Sato A, Nomura T, Sakakibara S, Inoue T, Tadokoro T, Anraku Y, Yumoto K, Tian C, Fukuhara H, Sasaki M, Orba Y, Shiwa N, Iwata N, Nagata N, Suzuki T, Sasaki J, Sekizuka T, Tonouchi K, Sun L, Fukushi S, Satofuka H, Kazuki Y, Oshimura M, Kurosaki T, Kuroda M, Matsuura Y, Suzuki T,  Sawa H, Hashiguchi T, Maenaka K, Takahashi Y: A SARS-CoV-2 antibody broadly neutralizes SARS-related coronaviruses and variants by coordinated recognition of a virus vulnerable site. Immunity Aug 24:S1074-7613(21)00359-9, 2021.
  28. Baidya S, Nishimoto Y, Sato S, Shimada Y, Sakurai N, Nonaka H, Noguchi K, Kido M, Tadano S, Ishikawa K, Li K, Okubo A, Yamada T, Orba Y, Sasaki M, Sawa H, Miyamoto H, Takada A, Nakamura T, Takaoka A: Dual effect of organogermanium compound THGP on RIG-I-mediated viral sensing and viral replication during influenza a virus infection. Viruses Aug 24;13(9):1674, 2021.
  29. Sasaki M, Kishimoto M, Itakura Y, Tabata K, Intaruck K, Uemura K, Toba S, Sanaki T, Sato A, Hall WW, Orba Y, Sawa H. Air-liquid interphase culture confers SARS-CoV-2 susceptibility to A549 alveolar epithelial cells. Biochem Biophys Res Commun Sep 10;577:146-151, 2021.
  30. Kariwa H, Sawa H, Kobayashi S: Inactivation of SARS-CoV-2 by povidone-iodine products: implications for effective mouth rinsing and gargling. Jpn J Vet Res Aug 69 (3) 183-187, 2021
  31. Yoo JS, Sasaki M, Cho SX, Kasuga Y, Zhu B, Ouda R, Orba Y, de Figueiredo P, Sawa H, Kobayashi KS. SARS-CoV-2 inhibits the MHC class I pathway by targeting the STAT1-IRF1-NLRC5 axis.  Nat Commun Nov 15;12(1):6602, 2021
  32. Chitanga S, Chambaro HM, Moonga LC, Hayashida K, Yamagishi J, Muleya W, Changula K, Mubemba B, Simbotwe M, Squarre D, Fandam P, Nalubamba KS, Qiu Y, Sawa H, Simulundu E: Rickettsia lusitaniae in Ornithodoros porcinus ticks, Zambia.  Pathogens Oct 12;10(10):1306, 2021

  33. Ohno M, Sasaki M, Orba Y, Sekiya T, Masum MA, Ichii O, Sawamura T, Kakino A,  Suzuki Y, Kida H, Sawa H*, Shingai M*: Abnormal blood coagulation and kidney damage in aged hamsters infected with severe acute respiratory syndrome coronavirus 2. Viruses 13(11), 2137, 2021

  34. Chambaro HM, Sasaki M, Muleya W, Kajihara M, Shawa M, Mwape KE, Harima H, Qiu Y, Hall WW, Fandamu P, Squarre D, Simulundu E, Sawa H*, Orba Y: Hepatitis E Virus Infection in Pigs: A First Report from Zambia. Emerg Microbes Infect Dec;10(1):2169-2172, 2021

  35. Qiu Y, Squarre D, Nakamura Y, Lau ACC, Moonga LC, Kawai N, Ohnuma A, Hayashida K, Nakao R, Yamagishi J, Sawa H, Namangala B, Kawabata H: Evidence of Borrelia theileri in wild and domestic animals in the Kafue ecosystem of Zambia. Microorganisms Nov 22;9(11):2405, 2021
  36. Phonera MC, Simuunza MC, Kainga H, Ndebe J, Chembensofu M, Chatanga E, Kanyanda S, Changula K, Muleya W, Mubemba B, Chitanga S, Kajihara M, Sawa H, Njunga G, Takada A, Simulundu E: Seroprevalence and risk factors of Crimean-Congo hemorrhagic fever in cattle of smallholder farmers in central Malawi. Pathogens Dec 10;10(12):1613, 2021
  37. Kalonda A, Phonera M, Saasa N, Kajihara M, Sutcliffe CG, Sawa H, Takada A, Simulundu E. Influenza A and D viruses in non-human mammalian hosts in Africa: A systematic review and meta-analysis. Viruses. Dec 2;13(12):2411, 2021

2020

  1. Simulundu E, Kapata N, Mupeta F, Chanda-Kapata P, Saasa N, Changula K, Muleya W, Chitanga S, Chambaro H, Mubemba B, Kajihara M, Chanda D, Mulenga L, Fwoloshi S, Shibemba AL, Kapaya F, Zulu P, Musonda K, Monze M, Sinyange N, Liwewe MM, Kapin’a M, Chipimo PJ, Ngosa W, Morales AN, Kayeyi N, Tembo J, Bates M, Orba Y, Sawa H, Takada A, Nalubamba KS, Malama K, Mukonka V, Zumula A: First COVID-19 case in Zambia
    -Comparative phylogenomic analyses of SARS-CoV-2 detected in African countries. Int J Infect Dis Jan;102:455-459, 2021

  2. Harima H, Sasaki M, Kajihara M, Mori-Kajihara A, Hang’ombe BM, Changula K, Orba Y, Ogawa H, Simuunza M, Yoshida R, Mweene A, Takada A, Sawa H*: Detection of novel orthoreovirus genomes in shrew (Crocidura hirta) and fruit bat (Rousettus aegyptiacus). J Vet Med Sci Feb 4;82(2):162-167, 2020

  3. Kobayashi S, Yoshii K, Phongphaew W, Muto M, Hirano M, Orba Y, Sawa H, Kariwa H: West Nile virus capsid protein inhibits autophagy by AMP-activated protein kinase degradation in neurological disease development. PLoS Pathog Jan 23; 16(1): e1008238, 2020

  4. Harima H, Kajihara M, Simulundu E, Bwalya E, Qiu Y, Isono M, Okuya K, Gonzalez G, Yamagishi J, Hang’ombe BM, Sawa H, Mweene AS, Takada A: Genetic and biological diversity of porcine Sapeloviruses prevailing in Zambia. Viruses Feb 5;12(2). 2020
  5. Simulundu E, Ndashe K, Chambaro HM, Squarre D, Reilly PM, Chitanga S, Changula K, Mukubesa AN, Ndebe J, Tembo J, Kapata N, Bates M, Sinkala Y, Hang’ombe BM, Nalubamba KS, Kajihara M, Sasaki M, Orba Y, Takada A, Sawa H: West Nile Virus in Farmed Crocodiles, Zambia, 2019. Emerg Infect Dis Apr;26(4):811-814, 2020
  6. Freitas IT, Tinago W, Sawa H, McAndrews J, Doak B, Prior-Fuller C, Sheehan G, Lambert JS, Muldoon E, Cotter AG, Hall WW, Mallon PWG, Carr MJ: Interferon lambda rs368234815 ΔG/ΔG is associated with higher CD4+:CD8+ T-cell ratio in treated HIV-1 infection. AIDS Res Ther Apr 15;17(1):13, 2020 

  7. Torii S, Orba Y, Sasaki M, Tabata K, Wada Y, Carr M, Hobson-Peters J, Hall RA, Takada A, Fukuhara T, Matsuura Y, Hall WW, Sawa H*: Host ESCRT factors are recruited during chikungunya virus infection and are required for the intracellular viral replication cycle. J Biol Chem Jun 5;295(23):7941-7957, 2020

  8. Kobayashi S, Kaneko C, Kawakami R, Hasebe R, Sawa H, Yoshii K, Kariwa H: Amino acid 159 of the envelope protein affects viral replication and T-cell infiltration by West Nile virus in intracranial infection. Sci Rep Apr 28;10(1):7168, 2020

  9. Chambaro HM, Sasaki M, Sinkala Y, Gonzalez G, Squarre D, Fandamu P, Lubaba C, Mataa L, Shawa M, Mwape KE, Gabrië S, Chembensofu M, Carr MJ, Hall WW, Qiu Y, Kajihara M, TakadaA, Orba Y, Simulundu E*, Sawa H*: Evidence for exposure of asymptomatic domestic pigs to African Swine fever virus during an inter-epidemic period in Zambia. Transbound Emerg Dis Nov 67:2741–2752, 2020

  10. Harima H, Sasaki M, Kajihara M, Gonzalez G, Simulundu E, Bwalya EC, Qiu Y, Okuya K, Isono M, Orba Y, Takada A, Hang’ombe BM, Mweene AS, Sawa H*: Characterization of mammalian orthoreoviruses isolated from feces of pigs in Zambia. J Gen Virol Oct;101(10):1027-1036, 2020

  11. Takahashi T, Inukai M, Sasaki M, Potratz M, Jarusombuti S, Fujii Y, Nishiyama S, Finke S, Yamada K, Sakai H, Sawa H, Nishizono A, Sugiyama M, Ito N: Genetic and phenotypic characterization of a rabies virus strain isolated from a dog in Tokyo, Japan in the 1940s. Viruses Aug 20;12(9):E914, 2020
  12. Chambaro HM*, Sasaki M, Simulundu E*, Silwamba I, Sinkala Y, Gonzalez G, Squarre D, Fandamu P, Lubaba CH, Munyeme M, Maseko M, Chimvwele C, Mataa L, Mooya LE, Mukubesa AN, Harima H, Samui KL, Muang’andu HM, Simuunza M, Nalubamba KS, Qiu Y, Carr MJ, Hall WW, Eshita Y, Sawa H, Orba Y*: Co-Circulation of multiple serotypes of bluetongue virus in Zambia. Viruses Aug 31;12(9): E963, 2020
  13. Qiu Y, Kajihara M, Nakao R, Mulenga E, Harima H, Hang’ombe BM, Eto Y, Changula K, Mwizabi D, Sawa H, Higashi H, Mweene A, Takada A, Simuunza M, Sugimoto C*: Isolation of Candidatus Bartonella rousetti and other bat-associated Bartonellae from bats and their flies in Zambia. Pathogens Jun 13;9(6):469, 2020
  14. Kalonda A, Saasa N, Nkhoma P, Kajihara M, Sawa H, Takada A, Simulundu E: Avian influenza viruses detected in birds in Sub-Saharan Africa: A systematic review. Viruses Sep 7;12(9): E993, 2020
  15. Wastika CE, Harima H, Sasaki M, Hang’ombe BM, Eshita Y, Qiu Y, Hall WW, Wolfinger MT*, Sawa H, Orba Y*: Discoveries of exoribonuclease-resistant structures of insect-specific flaviviruses isolated in Zambia. Viruses Sep 11;12(9):1017, 2020
  16. Fujiki J, Furuwa T, Munby M, Kawaguchi C, Matsuda Y, Shiokura Y, Nakamura K, Nakamura T, Sasaki M, Usui M, Iwasaki T, Gondaira S, Higuchi H, Sawa H, Tamura Y, Iwano H*: Susceptibility of Pseudomonas aeruginosa veterinary isolates against pbunavirus PB1-like phages. Microbiol Immunol Nov;64(11):778-782, 2020
  17. Runtuwene LR, Kawashima S, Pijoh VD, Tuda JSB, Hayashida K, Yamagishi J, Sugimoto C, Nishiyama S, Sasaki M, Orba Y, Sawa H, Takasaki T, James AA, Kobayashi T, Eshita Y: The lethal(2)-essential-for-life [L(2)EFL] gene family modulates dengue virus infection in Aedes aegypti. Int J Mol Sci Oct 12;21(20):7520, 2020
  18. Munby M, Fujiki J, Aoki K, Kawaguchi C, Nakamura K, Nakamura T, Sasaki M, Sato T, Usui M, Sawa H, Yokota Si, Tamura Y, Iwano H: Whole-Genome Sequence of Fluoroquinolone-resistant Escherichia coli, HUE1, isolated in Hokkaido, Japan.  Microbiol Resour Announc Nov 12;9(46):e01135-20, 2020
  19. Nobori H, Uemura K, Toba S, Sanaki T, Shishido T, Hall WW, Orba Y, Sawa H, Sato A: Identification of quinolone derivatives as effective anti-Dengue virus agents.  Antiviral Res Dec; 184:104969, 2020

2019

  1. Qiu Y, Nakao R, Hang’ombe BM, Sato K, Kajihara M, Kanchela S, Changula K, Eto Y, Ndebe J, Sasaki M, Thu MJ, Takada A, Sawa H, Sugimoto C, Kawabata H: Human Borreliosis Caused by a New World Relapsing Fever Borrelia-like Organism in the Old World. Clin Infect Dis. Jun 18;69(1):107-112, 2019

  2. Torii S, Matsuno K, Qiu Y, Mori-Kajihara A, Kajihara M, Nakao R, Nao N, Okazaki K, Sashika M, Hiono T, Okamatsu M, Sakoda Y, Ebihara H, Takada A, Sawa H: Infection of newly identified phleboviruses in ticks and wild animals in Hokkaido, Japan indicating tick-borne life cycles. Ticks Tick Borne Dis. Feb;10(2):328-335, 2019

  3. Kobayashi A, Qi Z, Shimazaki T, Munesue Y, Miyamoto T, Isoda N,Sawa H, Aoshima K, Kimura T, Mohri S, Kitamoto T, Yamashita T, Miyoshi I: Ganglioside Synthase Knockout Reduces Prion Disease Incubation Time in Mouse Models. Am J Pathol. Mar;189(3):677-686, 2019

  4. Anindita PD, Sasaki M*, Gonzalez G, Phongphaew W, Carr M, Bernard M. Hang’ombe BM, Mweene AS, Ito K, Orba Y, Sawa H: Discovery and genetic characterization of diverse smacoviruses in Zambian non-human primates.Sci Rep. Jun 6;9(1):8502, 2019

  5. Kobayashi A, Iwasaki Y, Takao M, Saito Y, Iwaki T, Qi Z, Torimoto R, Shimazaki T, Munesue Y, Isoda N, Sawa H, Aoshima K, Kimura T, Kondo H, Mohri S, Kitamoto T: A Novel Combination of Prion Strain Co-Occurrence in Patients with Sporadic Creutzfeldt-Jakob Disease. Am J Pathol. Jun;189(6):1276-1283, 2019

  6. Kajihara M, Hang’ombe BM, Changula K, Harima H, Isono M, Okuya K, Yoshida R, Mori-Kajihara A, Eto Y, Orba Y, Ogawa H, Qiu Y, Sawa H, Simulundu E, Mwizabi D, Munyeme M, Squarre D, Mukonka V, Mweene A, Takada A: Marburgvirus in Egyptian Fruit Bats, Zambia. Emerg Infect Dis. Aug 17;25(8), 2019.

  7. Hayashida K, Orba Y, Sequeira PC, Sugimoto C, Hall WW, Eshita Y, Suzuki Y, Runtuwene L, Brasil P, Calvet G, Rodrigues CDS, Santos CCD, Mares-Guia MAM, Yamagishi J*, Filippis AMB, Sawa H*: Field diagnosis and genotyping of chikungunya virus using a dried reverse transcription loop-mediated isothermal amplification (LAMP) assay and MinION sequencing. PLoS Negl Trop Dis. Jun 3;13(6): e0007480, 2019

  8. Qiu Y, Kajihara M, Harima H, Hang’ombe BM, Nakao R, Hayashida K, Mori-Kajihara A, Changula K, Eto Y, Ndebe J, Yoshida R, Takadate Y, Mwizabi D, Kawabata H, Simuunza M, Mweene A, Sawa H, Takada A, Sugimoto C: Molecular characterization and phylogenetic analysis of Trypanosomaspp. detected from striped leaf-nosed bats (Hipposideros vittatus) in Zambia. Int J Parasitol Parasites Wildl. Apr 27;9: 234-238, 2019

  9. Wastika CE, Sasaki M, Yoshii K, Anindita PD, Hang’ombe BM, Mweene AS, Kobayashi S, Kariwa H, Carr MJ, Hall WW, Eshita Y, Orba Y, Sawa H*: Serological evidence of Zika virus infection in non-human primates in Zambia. Arch Virol. 164(8): 2165-2170, 2019

  10. Muleya W, Chambaro HM, Sasaki M, Gwenhure LF, Mwenechanya R, Kajihara M, Saasa N, Mupia Z, Mori-Kajihara A, Qiu Y, Kanguwa E, Mweene A, Namangala B, Takada A, Sawa H: Genetic diversity of rabies virus in different host species and geographic regions of Zambia and Zimbabwe. Virus Gene. 55(5): 713-719, 2019

  11. Halawi AD, Saasa N, Pongombo BL, Kajihara M, Chambaro HM, Hity M, Sawa H, Takada A, Mweene AS, Nsembo LL, Simulundu E: Seroprevalence of Rift Valley fever in cattle of smallholder farmers in Kwilu Province in the Democratic Republic of Congo. Trop Anim Health Prod. Nov;51(8):2619-2627, 2019

  12. Carr M, Gonzalez G, Martinelli A, Wastika CE, Ito K, Orba Y, Sasaki M, Sawa H: Increased expression of the antioxidant sestrin 2 identified by RNA-seq transcriptomic analysis of Japanese encephalitis virus-infected neuronal cells. Virus Gene. Oct;55(5):630-642, 2019

  13. Tanikawa S, Tanino M, Wang L, Ishikawa M, Miyazaki M, Tsuda M, Orba Y, Sawa H, Matoba K, Nakamura N, Nagashima K, Hall WW, Tanaka S: Autopsy findings in the early stage of amyotrophic lateral sclerosis with “dropped head” syndrome. Neuropathology. 2019 Oct;39(5):374-377, 2019.

  14. Watanabe T, Suzuki N, Tomonaga K, Sawa H, Matsuura Y, Kawaguchi Y, Takahashi H, Nagasaki K, Kawaoka Y: Neo-virology: The raison d’etre of viruses. Virus Res. Dec; 274:197751, 2019

  15. Sanaki T, Wakabayahi M, Yoshioka T, Yoshida R, Shishido T, Hall WW, Sawa H, Sato A: Inhibition of dengue virus infection by 1-stearoyl-2-arachidonoyl-phosphatidylinositol in vitro. FASEB J. 33(12):13866-13881, 2019

2018

  1. Sasaki M, Anindita PD, Phongphaew W, Carr M, Kobayashi S, Orba Y, Sawa H*: Development of a rapid and quantitative method for the analysis of viral entry and release using a NanoLuc luciferase complementation assay. Virus Res. Jan 2; 243:69-74, 2018

  2. Ogawa H, Kajihara M, Nao N, Shigeno A, Fujikura D, Hang’ombe BM, Mweene AS, Mutemwa A, Squarre D, Yamada M, Higashi H, Sawa H, Takada A: Characterization of a Novel Bat Adenovirus Isolated from Straw-Colored Fruit Bat (Eidolon helvum). Viruses. Dec 4; 9(12). pii: E371, 2017

  3. Wada Y, Sasaki M, Setiyono A, Handharyani E, Rahmadani I, Taha S, Adiani S, Latief M, Kholilullah ZA, Subangkit M, Kobayashi S, Nakamura I, Kimura T, Orba Y, Sawa H*: Detection of novel gammaherpesviruses from fruit bats in Indonesia. J Med Microbiol. Mar; 67(3): 415-422, 2018

  4. Munesue Y, Shimazaki T, Qi Z, Isoda N, Sawa H, Aoshima K, Kimura T, Mohri S, Kitamoto T, Kobayashi A: Development of a quick bioassay for the evaluation of transmission properties of acquired prion diseases. Neurosci Lett. Mar 6;668:43-47, 2018

  5. Sasaki M, Anindita PD, Ito N, Sugiyama M, Carr M, Fukuhara H, Ose T, Maenaka K, Takada A, Hall WW, Orba Y, Sawa H*: Heparan sulfate proteoglycans serve as an attachment factor for rabies virus entry and infection. J Infect Dis. May 5;217(11): 1740-1749, 2018

  6. Anindita PD, Sasaki M*, Okada K, Ito N, Sugiyama M, Saito-Tarashima N, Minakawa N, Shuto S, Otsuguro S, Ichikawa S, Matsuda A, Maenaka K, Orba Y, Sawa H*: Ribavirin-related compounds exert in vitro inhibitory effects toward rabies virus. Antiviral Res. Jun 28; 154: 1-9, 2018

  7. Qiu Y, Kaneko C, Kajihara M, Ngonda S, Simulundu E, Muleya W, Thu MJ, Hang’ombe MB, Katakura K, Takada A, Sawa H, Simuunza M, Nakao R: Tick-borne haemoparasites and Anaplasmataceae in domestic dogs in Zambia. Ticks Tick Borne Dis. May 9(4):988-995, 2018

  8. Orba Y, Hang’mbe BM, Mweene AS, Wada Y, Anindita PD, Phongphaew W, Qiu Y, Kajihara M, Mori-Kajihara A, Eto Y, Sasaki M, Hall WW, Sawa H*: First isolation of West Nile virus in Zambia from mosquitoes. Transbound Emerg Dis. Aug 65(4):933-938, 2018

  9. Torii S, Orba Y*, Hang’mbe BM, Mweene AS, Wada Y, Anindita PD, Wallaya P, Qiu Y, Kajihara M, Mori-Kajihara A, Eto Y, Harima H, Sasaki M, Carr M, Hall WW, Eshita Y, Abe T, Sawa H*: Discovery of Mwinilunga alphavirus: a novel alphavirus in Culex mosquitoes in Zambia. Virus Res. May 2; 250: 31-36, 2018

  10. Nobori H, Toba S, Yoshida R, Hall WW, Orba Y, Sawa H, Sato A: Identification of Compound-B, a novel anti-Dengue virus agent targeting the non-structural protein 4A. Antivirus Res. Jul;155:60-66, 2018

  11. Tazaki T, Tabata K, Ainai A, Ohara Y, Kobayashi S, Ninomiya T, Orba Y, Mitomo H, Nakano T, Hasegawa H, Ijiro K, Sawa H, Suzuki T, Niikura K: Shape-dependent adjuvanticity of nanoparticle-conjugated RNA adjuvants for intaranasal inactivatd influenza vaccines. RSC Adv. May 8, 16527-16536, 2018

  12. Sasaki M*, Kajihara M, Changula K, Mori-Kajihara A, Ogawa H, Hang’ombe B, Mweene AS, Simuunza M, Yoshida R, Carr M, Orba Y, Takada A, Sawa H*:Identification of group A rotaviruses from Zambian fruit bats provides evidence for long-distance transmission events in Africa. Infect Genet Evol. Sep63:104-109, 2018

  13. Matsuno K, Kajihara M, Nakao R, Nao N, Mori-Kajihara A, Muramatsu M, Qiu Y, Torii S, Igarashi M, Kasajima N, Mizuma K, Yoshii K, Sawa H, Sugimoto C, Takada A, Ebihara H: The unique phylogenetic 1 position of a novel tick-borne phlebovirus ensures an ixodid origin of the genus Phlebovirus. mSphere. Jun 13;3(3), pii: e00239-18, 2018

  14. Fujiki J, Nobori H, Sato A, Sasaki M, Carr M, Hall WW, Orba Y, Sawa H*: Single amino acid mutation in dengue virus NS4B protein has opposing effects on viral proliferation in mammalian and mosquito cells. Jpn J Infect Dis. Nov 22;71(6):448-454, 2018

  15. Ishida Y, Tsuda M, Sawamura Y, Fujii K, Murai H, Horiuchi N, Orba Y, Sawa H, Hall WW, Nagashima K, Tanaka S: Integrated diagnosis of pilocytic astrocytoma: Molecular diagnostic procedure for an unusual case. Pathol Int. Dec;68(12):694-699, 2018

2017

  1. Nakao R, Matsuno K, Qiu Y, Maruyama J, Eguchi N, Nao N, Kajihara M, Yoshii K, Sawa H, Takada A, Sugimoto C. Putative RNA viral sequences detected in an Ixodes scapularis-derived cell line. Ticks Tick Borne Dis. Jan;8(1):103-111, 2017

  2. Carr M, Kawaguchi A, Sasaki M, Gonzalez G, Ito K, Thomas Y, Hang’ombe BM, Mweene AS, Zhao G, Wang D, Orba Y, Ishii A, Sawa H*: Isolation of a simian immunodeficiency virus from a malbrouck (Chlorocebus cynosuros). Arch Virol. Feb;162(2):543-548, 2017

  3. Phongphaew W, Kobayashi S, Sasaki M, Carr M, Hall WW, Orba Y, Sawa H*: Valosin-containing protein (VCP/p97) plays a role in the replication of West Nile virus. Virus Res. Jan 15;228: 114-123, 2017

  4. Gonzalez G, Sasaki M, Kamiya T, Burkitt-Gray L, Tsuji NM, Sawa H, Ito K: An optimistic protein assembly from sequence reads salvaged an uncharacterized segment of mouse picobirnavirus. Sci Rep. Jan 10;7:40447, 2017

  5. Wada Y, Orba Y, Sasaki M, Kobayashi S, Carr MJ, Nobori H, Sato A, Hall WW, Sawa H*: Discovery of a novel antiviral agent targeting the nonstructural protein 4 (nsP4) of chikungunya virus. Virology, May;505:102-112, 2017

  6. Carr M, Gonzalez G, Sasaki M, Ito K, Ishii A, Hang’ombe BM, Mweene AS, Orba Y, Sawa H*: Discovery of African bat polyomaviruses and infrequent recombination in the large T antigen in the Polyomaviridae. J Gen Virol. 98(4): 726-738, 2017

  7. Akkina R, Ellerbrok H, Hall W, Hasegawa H, Kawaguchi Y, Kleanthous H, McSweegan E, Mercer N, Romanowski V, Sawa H, Vahlne A: 2016 International meeting of the Global Virus Network. Antiviral Res. Mar 16; 142:21-29, 2017

  8. Matsuno K, Orba Y, Maede-White K, Scott D, Feldmann F, Liang M, Ebihara H: Animal Models of Emerging Tick-Borne Phleboviruses: Determining Target Cells in a Lethal Model of SFTSV Infection. Front Microbiol. 8:104, 2017

  9. Takagi Y, Matsui K, Nobori H, Maeda H, Sato A, Kurosu T, Orba Y, Sawa H, Hattori K, Higashino K, Numata Y, Yoshida Y: Discovery of novel cyclic peptide inhibitors of dengue virus NS2B-NS3 protease with antiviral activity. Bioorg Med Chem Lett. Aug 27 (15): 3586-3590, 2017

  10. Hasebe R, Nakao R, Ohnuma A, Yamasaki T, Sawa H, Takai S, Horiuchi M: Listeria monocytogenes serotype 4b strains replicate in monocytes/macrophages more than the other serotypes. J Vet Med Sci. Jun 10;79 (6):962-969, 2017

  11. Carr M, Gonzalez G, Sasaki M, Dool SE, Ito K, Ishii A, Hang’ombe BM, Mweene AS, Teeling EC, Hall WW, Orba Y, Sawa H*: Identification of the same polyomavirus species in different African horseshoe bat species is indicative of short-range host-switching events. J Gen Virol. 98(11):2771-2785, 2017

2016

  1. Kobayashi S, Suzuki T, Kawaguchi A, Phongphaew W, Yoshii K, Iwano T, Harada A, Kariwa H, Orba Y, Sawa H*：Rab8b regulates transport of West Nile virus particles from recycling endosomes.　J Biol Chem, 291(12):6559-6568, 2016

  2. Anindita PD, Sasaki M, Nobori H, Sato A, Carr M, Ito N, Sugiyama M, Orba Y, Sawa H*: Generation of recombinant rabies viruses encoding NanoLuc luciferase for antiviral activity assays. Virus Res, 215: 121-128, 2016 (* corresponding author)

  3. Sasaki M, Gonzalez G, Wada Y, Setiyono A, Handharyani E, Rahmadani I, Taha S, Adiani S, Latief M, Kholilullah ZA, Subangkit M, Kobayashi S, Nakamura I, Kimura T, Orba Y, Ito K, Sawa H*: Divergent bufavirus harboured in megabats represent a new lineage of parvoviruses. Sci Rep, 6:24257, 2016

  4. Sasaki M, Orba Y, Sasaki S, Gonzalez G, Ishii A, Hangombe BM, Mweene AS, Ito K, Sawa H*: Multireassortant G3P[3] group A rotavirus in a horseshoe bat in Zambia. J Gen Virol. 97(10):2488-2493, 2016

2015

  1. Makino Y, Tsuda M, Ohba Y, Nishihara H, Sawa H, Nagashima k, Tanaka S: Tyr724 phosphorylation of ELMO1 by Src is involved in cell spreading and migration via Rac1 activation. Cell Commun Signal. 13:35, 2015
  2. Aoshima K, Inoue E, Sawa H, Okada Y: Paternal H3K4 methylation is required for minor zygotic gene activation and early mouse embryonic development. EMBO Rep. 16(7):803-812, 2015

  3. Sasaki M, Orba Y, Anindita PD, Ishii A, Ueno K, Hang’ombe BM, Mweene AS, Ito K, Sawa H*: Distinct lineages of bufavirus in wild shrews and nonhuman primates. Emerg Infect Dis. 21(7):1230-1233, 2015

  4. Ogawa H, Koizumi N, Ohnuma A, Mutemwa A, Hang’ombe BM, Mweene AS, Takada A, Sugimoto C, Suzuki Y, Kida H, Sawa H*: Molecular epidemiology of pathogenic Leptospira spp. in the straw-colored fruit bat (Eidolon helvum) migrating to Zambia from the Democratic Republic of Congo. Infect Genet Evol. Jun 32:143-147, 2015
  5. Orba Y, Sasaki M, Yamaguchi H, Ishii A, Thomas Y, Ogawa H, Hang’ombe BM, Mweene AS, Morikawa S, Saijo M, Sawa H*: Orthopoxvirus infection among wildlife in Zambia. J Gen Virol. 96(Pt 2):390-4, 2015
  6. Sasaki M, Orba Y, Ueno K, Ishii A, Moonga L, Hang’mbe BM, Mweene AS, Ito K, Sawa H*: Metagenomic analysis of the shrew enteric virome reveals novel viruses related to human stool-associated viruses. J Gen Virol. 96(Pt 2):440-52, 2015
  7. Yabe J, Hamambulu P, Simulundu E, Ogawa H, Kajihara M, Mori-Kajihara A, Changula-Chitanga K, Mwase M, Mweemba-Muwowo M, Chambaro HM, Mataa L, Hang’ombe B, Namangala B, Fandamu P, Sawa H, Takada A, Higashi H, Mweene AS: Pathological and molecular diagnosis of the 2013 African swine fever outbreak in Lusaka, Zambia. Trop Anim Health Prod. 47(2):459-63, 2015
  8. Ogawa H., Miyamoto H, Nakayama E, Yoshida R, Nakamura I, Sawa H, Ishii A, Thomas Y, Nakagawa E, Matsuno K, Kajihara M, Maruyama J, Nao N, Muramatsu M, Kuroda M, Simulundu E, Changula K, Hang’ombe B, Namangala B, Nambota A, Katampi J, Igarashi M, Ito K, Feldmann H, Sugimoto C, Moonga L, Mweene A, Takada A: Seroepidemiological prevalence of multiple species of filoviruses in fruit bats (Eidolon helvum) migrating in Africa. J Infect Dis. 1;212 (2015)
  9. Kobayashi S, Sasaki M, Nakao R, Setiyono A, Handharyani E, Orba Y, Rahmadani I, Taha S, Adiani S, Subangkit M, Nakamura I, Kimura T*, Sawa H* Detection of novel polyomaviruses in fruit bats in Indonesia. Arch Virol. 160(4):1075-82
  10. Anindita PD, Sasaki M, Setiyono A, Handharyani E, Orba Y, Kobayashi S, Rahmadani I, Taha S, Adiani S, Subangkit M, Nakamura I, Sawa H*, Kimura T* Detection of coronavirus genomes in Moluccan naked-backed fruit bats in Indonesia. Arch Virol. 160(4):1113-8

2014

  1. Sasaki M, Muleya W, Ishii A, Orba Y, Hangombe BM, Mweene AS, Moonga L, Thomas Y, Kimura T, Sawa H*: Molecular epidemiology of paramyxoviruses in Zambian wild rodents and shrews. J Gen Virol 95(Pt 2):325-330, 2014 (* corresponding author)
  2. Muleya W, Sasaki M, Orba Y, Ishii A, Thomas Y, Nakagawa M, Ogawa H, Hangombe B, Namangala B, Mweene A, Takada A, Kimura T, Sawa H*: Molecular epidemiology of paramyxoviruses in frugivorous Eidolon helvum bats in Zambia. J Vet Med Sci 76(4):611-614, 2014 (* corresponding author)
  3. Kesdangsakonwut S, Sunden Y, Aoshima K, Iwaki Y, Okumura M, Sawa H, Umemura T: Survival of rabid rabbits after intrathecal immunization. Neuropathology (in press)
  4. Yamaguchi H, Kobayashi S, Maruyama J, Sasaki M, Takada A, Kimura T, Sawa H*, Orba Y: Role of the C-Terminal Region of Vervet Monkey Polyomavirus 1 VP1 in Virion Formation. J Vet Med Sci 76(5):637-644, 2014 (* corresponding author)
  5. Simulundu E, Nao N, Yabe J, Muto NA, Sithebe T, Sawa H, Manzoor R, Kajihara M, Muramatsu M, Ishii A, Ogawa H, Mweene AS, Takada A: The zoonotic potential of avian influenza viruses isolated from wild waterfowl in Zambia. Arch Virol 159(10):233-2640, 2014
  6. Sasaki M, Setiyono A, Handharyani E, Kobayashi S, Rahmadani I, Taha S, Adiani S, Subangkit M, Nakamura I, Sawa H, Kimura T: Isolation and Characterization of A Novel Alphaherpesvirus in Fruit Bats. J Virol 88(17):9819-9829, 2014
  7. Kobayashi S, Orba Y, Yamaguchi H, Takahashi K, Sasaki M, Hasebe R, Kimura T, Sawa H*. Autophagy inhibits viral genome replication and gene expression stages in West Nile virus infection. Virus Res 191: 83-91, 2014 (* corresponding author)
  8. Nakayima J, Hayashida K, Nakao R, Ishii A, Ogawa H, Nakamura I, Moonga L, Hang Ombe BM, Mweene AS, Thomas Y, Orba Y, Sawa H, Sugimoto C. Detection and characterization of zoonotic pathogens of free-ranging non-human primates from Zambia. Parasit Vectors Oct 29; 7(1):490, 2014
  9. Kesdangsakonwut S, Sunden Y, Yamada K, Nishizono A, Sawa H, Umemura T. Neurogenic cardiomyopathy in rabbits with experimentally induced rabies. Vet Pathol (in press)
  10. Ishii A, Ueno K, Orba Y, Sasaki M, Moonga L, Hang’ombe BM, Mweene AS, Umemura T, Ito K, Hall WW, Sawa H: A nairovirus isolated from African bats causes haemorrhagic gastroenteritis and severe hepatic disease in mice. Nat Commun 5:5651, 1-11, 2014

2013

  1. Suzuki T, Orba Y, Makino Y, Okada Y, Sunden Y, Hasegawa H, Hall WW, Sawa H: Viroporin activity of the JC polyomavirus is regulated by interactions with the adaptor protein complex 3. Proc Natl Acad Sci USA 110(46):18668-18673, 2013
  2. Sasaki M, Ishii A, Orba Y, Thomas Y, Hang’ombe BM, Moonga L, Mweene AS, Ogawa H, Nakamura I, Kimura T, Sawa H: Human parainfluenza virus type 3 in wild primates, Zambia. Emerg Infect Dis 19 (9): 1500-1503, 2013
  3. Yamaguchi H, Kobayashi S, Ishii A, Ogawa H, Nakamura I, Moonga L, Hang’ombe BM, Mweene AS, Thomas Y, Kimura T, Sawa H, Orba Y: Identification of a novel polyomavirus from vervet monkeys in Zambia. J Gen Virol 94(Pt 6): 1357-1364, 2013
  4. Kobayashi S, Suzuki T, Igarashi M, Orba Y, Ohtake N, Nagakawa K, Niikura K, Kimura T, Kasamatsu H, Sawa H: Cysteine residues in the major capsid protein, Vp1, of the JC Virus are important for protein stability and oligomer formation. PLoS One 8 (10): e76668, 2013
  5. Makino Y, Suzuki T, Hasebyae R, Kimura T, Maeda A, Takahashi H, Sawa H: Establishment of tracking system for West Nile virus entry and evidence of microtubule involvement in particle transport. J Virol Methods 195:250-257, 2013
  6. Niikura K, Sugimura N, MusashiY, Mikuni S, Matsuo Y, Kobayashi S, Nagakawa K, Takahara S, Takeuchi C, Sawa H, Kinjo M, Ijiro K: Virus-like particles with removable cyclodextrins enable glutathione-triggered drug release in cells. Mol. BioSyst., 2013, 9, 501
  7. Niikura K, Matsunaga T, Suzuki T, Kobayashi S, Yamaguchi H, Orba Y, Kawaguchi A, Hasegawa H, Kajino K, Ninomiya T, Ijiro K, Sawa H: Gold nanoparticles as a vaccine platform: influence of size and shape on immunological responses in vitro and in vivo. ACS Nano 28; 7(5): 3926-3938, 2013
  8. Kimura T, Okumura M, Kim E,Sasaki M, Orba Y, Sawa H: Characterization of Japanese encephalitis virus infection in an immortalized mesencephalic cell line, CSM14.1. Microbiol Immunol 57 (10): 723-731, 2013
  9. Miura K, Wakayama Y, tanino M, Orba Y, Sawa H, Hatakeyama M, Tanaka S, Sabe H, Mochiziki N: Involvement of EphA2-mediated tyrosine phosphorylation of Shp2 in Shp2-regulated activation of extracellular signal-regulated kinase. Oncogene 1-10, 2013
  10. Takahashi K, Orba Y, Kimura T, Wang L, KohsakaS, Tsuda M, Tanino M, Nishihara H, Nagashima K, Sawa H, Tanaka S: Relationship between methyl CpG binding protein 2 and JC viral proteins. Jpn J Infect Dis 66, 126-132, 2013
  11. Nakamura I, Hang’ombe BM, Sawa H, Kobayashi S, Orba Y, Ishii A, Thomas Y, Isozumi R, Yoshimatsu K, Mweene AS, Takada A, Sugimoto C, Arikawa J. Cross-Reactivity of Secondary Antibodies against African Rodents and Application for Sero-Surveillance. J Vet Med Sci 75(6):819-825, 2013
  12. Kawai YK, Watanabe KP, Ishii A, Ohnuma A, Sawa H, Ikenaka Y, Ishizuka M: De novo sequence analysis of cytochrome P450 1-3 genes expressed in ostrich liver with highest expression of CYP2G19. Comp Biochem Physiol Part D Genomics Proteomics 8(3): 201-208, 2013
  13. Ikebe E, Kawaguchi A, Tezka K, Taguchi S, Hirose S, Matsumoto T, Mitsui T, Senba K, Nishizono A, Hori M, Hasegawa H, Yamada Y, Ueno T, Tanaka Y, Sawa H, Hall W, Minami Y, Jeang KT, Ogata M, Morishita K, Hasegawa H, Fujisawa J, Iha HH: A novel HSP90 inhibitor, 17-DMAG, induces Tax down-regulation and its oral administration to ATL-model mice intervenes against the infiltration property of the ATL-like lymphocytes and provides extended survival period. Blood Cancer J 3(8): e132, 2013

2012

  1. Muleya W, Namangala B, Mweene A, Zulu L, Fandamu P, Banda D, Kimura T, Sawa H, Ishii A: Molecular epidemiology and a loop-mediated isothermal amplification method for diagnosis of infection with rabies virus in Zambia. Virus Res. 163(1):160-168, 2012
  2. Kobayashi S, Orba Y, Yamaguchi H, Kimura T, Sawa H: Accumulation of ubiquitinated proteins is related to the West Nile virus-induced neuronal apoptosis. Neuropathology 32:398-405, 2012
  3. Nagakawa K, Niikura K, Suzuki T, Matsuo Y, Igarashi M, Sawa H, Ijiro K: Virus Capsid coating of gold nanoparticles via cysteine-Au interactions and their effective cellular uptakes. Chem. Lett. 41(1): 113-115, 2012
  4. Hang’ombe BM, Nakamura I, Samui KL, Kaile D, Mweene AS, Kilonzo BS, Sawa H, Sugimoto C, Wren BW: Evidence of Yersinia pestis DNA from fleas in an endemic plague area of Zambia. BMC Res. Notes 5(1):72, 2012
  5. Hang’ombe B, Mwansa J.C.L, Muwowo S, Mulenga P, Kapina M, Musenga E, Squarre D, Mataa L, Thomas S.Y,7, Ogawa H, Sawa H, Higashi H. Human – Animal Anthrax outbreak in the Luangwa valley of Zambia in 2011. Trop. Doct. 42(3): 136-139, 2012
  6. Fukuhara S, Simmons S, Kawamura S, Inoue A, Orba Y, Tokudome T, Sunden Y, Arai Y, Moriwaki K, Ishida J, Uemura A, Kiyonari H, Abe T, Fukamizu A, Hirashima M, Sawa H, Aoki J, Ishii M, Mochizuki N: The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice. J. Clin. Invest. 122(4): 1416-1426, 2012
  7. Dang X, Wüthrich C, Gordon J, Sawa H, Koralnik IJ: JC Virus Encephalopathy Is Associated with a Novel Agnoprotein-Deletion JCV Variant. PLoS One 7(4):e35793, 2012
  8. Furuta Y, Oridate N, Takeichi N, Fukuda S, Sawa H: Alpha-defensin overexpression in patients with Bell’s palsy and Ramsay Hunt syndrome. Ann. Otol. Rhinol. Laryngol. 121(6):419-25, 2012
  9. Muto NA, Sunden Y, hattori T, Fujikura D, Nakayama Y, Miyazaki T, Maruyama M, Kimura T, Sawa H: Pathological examination of lung tissues in influenza A virus-infected aged mice. Jpn. J. Infect. Dis. 65(5): 383-391, 2012
  10. Muto NA, Yoshida R, Suzuki T, Kobayashi S, Ozaki H, Fujikura D, Manzoor R, Muramatsu M, Takada A, Kimura T, Sawa H: Inhibitory effects of an M2-specific monoclonal antibody on different strains of influenza A virus. Jpn. J. Vet. Res. 60 (2&3): 71-83, 2012
  11. Ishii A, Thomas Y, Moonga L, Nakamura I, Ohnuma A, Hang’ombe B, Takada A, Mweene AS, Sawa H: Molecular surveillance and phylogenetic analysis of Old World Arenaviruses in Zambia. J. Gen. Virol. 93(Pt 10): 2247-2251, 2012
  12. Suzuki T, Semba S, Sunden Y, Orba Y, Kobayashi S, Nagashima K, Kimura T, Hasegawa H, Sawa H: Role of JC virus agnoprotein in virion formation. Microbiol Immunol. 56(9): 636-646, 2012
  13. Muleya W, Namangala B, Simuunza M, Nakao R, Inoue N, Kimura T, Ito K, Sugimoto C, Sawa H: Population genetic analysis and sub-structuring of Theileria parva in the northern and eastern parts of Zambia. Parasit. Vectors 5: 255, 2012
  14. Sasaki M, Setiyono A, Handharyani E, Rahmadani I, Taha S, Adiani S, Subangkit M, Sawa H, Nakamura I, Kimura T: Molecular detection of a novel paramyxovirus in fruit bats from Indonesia. Virol. J. 9:240, 2012

2011

  1. Shirai S, Takahashi K, Kohsaka S, Tsukamoto T, Isogai H, Kudo S, Sawa H, Nagashima K, Tanaka S: High expression of MeCP2 in JC virus-infected cells of progressive multifocal leukoencephalopathy brains. Neuropathology 31(1) 38-41, 2011
  2. Orba Y, Kobayashi S, Nakamura I, Ishii A, Hang’ombe BM, Mweene AS, Thomas Y, Kimura T, Sawa H*. Detection and characterization of a novel polyomavirus in wild rodents. J Gen Virol 92 (Pt 4) 789-795, 2011 (* corresponding author)
  3. Sasaki M, Hasebe R, Makino Y, Suzuki T, Fukushi H, Okamoto M, Matsuda K, Taniyama H, Sawa H, Kimura T: Equine Major Histocompatibility Complex Class I Molecules Act as Cellular Entry Receptors that Bind to Equine Herpesvirus-1 Glycoprotein D. Genes Cells 16(4):343-357, 2011
  4. Simulundu E, Ishii A, Igarashi M, Mweene AS, Suzuki Y, Hang’ombe BM, Namangala B, Moonga L, Manzoor R, Ito K, Nakamura I, Sawa H, Sugimoto C, Kida H, Simukonda C, Chansa W, Chulu J, Takada A: Characterization of influenza A viruses isolated from wild waterfowl in Zambia. J Gen Virol 92 (Pt 6):1416-1427, 2011
  5. Teramoto S, Kaiho M, Takano Y, Endo R, Kikuta H, Sawa H, Ariga T, Ishiguro N: Detection of KI polyomavirus and WU polyomavirus DNA by real-time PCR in nasopharyngeal swabs and in normal lung and lung adenocarcinoma tissues. Microbiol Immunol 55(7): 525-530, 2011
  6. Kim E, Okumura M, Sawa H, Miyazaki T, Fujikura D, Yamada S, Sugahara K, Sasaki M, Kimura T: Paradoxical effects of chondroitin sulfate-E on Japanese encephalitis viral infection. Biochem Biophys Res Commun 409(4):717-722, 2011
  7. Ishii A, Thomas Y, Moonga L, Nakamura I, Ohnuma A, Hang’ombe B, Takada A, Mweene A, Sawa H: Novel Arenavirus, Zambia. Emerg Infect Dis 17(10): 1921-1924, 2011
  8. Sasaki M, Kim E, Igarashi M, Ito K, Hasebe R, Fukushi H, Sawa H, Kimura T: A single amino acid residue in the α2 domain of major histocompatibility complex class I is involved in the efficiency of equine herpesvirus-1 entry. J Biol Chem 286 (45): 39370-39378, 2011
  9. Suzuki T, Ainai A, Nagata N, Sata T, Sawa H, Hasegawa H: A novel function of the N-terminal domain of PA in assembly of influenza A virus RNA polymerase. Biochem Biophys Res Commun 414 (4): 719-726, 2011

2010

  1. Ichinohe T, Ainai A, Nakamura T, Akiyama Y, Maeyama J, Odagiri T, Tashiro M, Takahashi H, Sawa H, Tamura S, Chiba J, Kurata T, Sata T, Hasegawa H: Induction of cross-protective immunity against influenza A virus H5N1 by intranasal vaccine with mycelia extracts of mushroom. J Med Virol 82 (1): 128-137, 2010
  2. Orba Y, Suzuki T, Makino Y, Kubota K, Tanaka S, Kimura T, Sawa H*: Large T antigen promotes JC virus replication in G2-arrested cells by inducing ATM- and ATR-mediated G2 checkpoint signaling. J Biol Chem 285 (2):1544-1554, 2010 (* corresponding author)
  3. Ohtake N, Niikura K, Suzuki T, Nagakawa K, Mikuni S, Matsuo Y, Kinjo M, Sawa H, Ijiro K: Low pH-triggered model drug molecule release from virus-like particles. Chembiochem 11(7):959-62, 2010
  4. Suzuki T, Orba Y, Okada Y, Sunden Y, Kimura T, Tanaka S, Nagashima K, Hall WW, Sawa H*: The Human Polyoma JC Virus Agnoprotein Acts as a Viroporin. PLoS Pathogens 6 (3):e1000801, 2010 (* corresponding author)
  5. Suzuki T, Yamanouchi S, Sunden Y, Orba Y, Kimura T, Sawa H*: Natalizumab has no direct biological effect on JC virus infectivity in permissive human neural cell lines. J Med Virol 82 (7):1229-1235, 2010 (* corresponding author)
  6. Watters KM, Dean J, Hasegawa H, Sawa H, Hall W, Sheehy N: Cytokine and growth factor expression by HTLV-1 Lck-tax transgenic cells in SCID mice. AIDS Res Hum Retroviruses 26 (5): 593-603, 2010
  7. Hasebe R, Suzuki T, Makino Y, Igarashi M, Yamanouchi S, Maeda A, Horiuchi M, Sawa H, Kimura T: Transcellular transport of West Nile virus-like particles across human endothelial cells depends on residues 156 and 159 of envelope protein. BMC Microbiol 10:165, 2010
  8. Kawaguchi A, Suzuki T, Kimura T, Sakai N, Ayabe T, Sawa H*, Hasegawa H*: Functional analysis of an α-helical antimicrobial peptide derived from a novel mouse defensin-like gene. Biochem Biophys Res Commun 398(4): 778-784, 2010 (* corresponding author)
  9. Kimura T, Sasaki M, Okumura M, Kim E, Sawa H: Flavivirus encephalitis: pathological aspects of mouse and other animal models. Vet Pathol 47(5): 806-818, 2010

2009

  1. Takahashi H, Kitagawa Y, Maeda-Satoh M, Hasegawa H, Sawa H, Sata T: Monoclonal antibody and siRNAs for topoisomerase I suppresses telomerase activity. Hybridoma 28(1): 63-65, 2009
  2. Kimura T, Sakai M, Tabu K, Wang L, Tsunematsu R, Tsuda M, Sawa H, Nagashima K, Nishihara H, Hatakeyama S, Nakayama K, Ladanyi M, Tanaka S, Nakayama KI: Human synovial sarcoma proto-oncogene Syt is essential for early embryonic development through the regulation of cell migration. Lab Invest 89(6): 645-656, 2009
  3. Kawaguchi A, Orba Y, Kimura T, Iha H, Ogata M, Tsuji T, Sata T, Hall WW, Sawa H*, Hasegawa H*: Inhibition of the SDF-1α-CXCR4 axis by the CXCR4 antagonist AMD3100 suppresses the migration of cultured cells from ATL patients and murine lymphoblastoid cells from HTLV-I Tax transgenic mice. Blood (* corresponding author) 114 (14): 2961-2968, 2009
  4. Simulundu E, Mweene AS, Tomabechi D, Hang’ombe BM, Ishii A, Suzuki Y, Nakamura I, Sawa H, Sugimoto C, Ito K, Kida H, Saiwana L, Takada A: Characterization of H3N6 avian influenza virus isolated from a wild white pelican in Zambia. Arch Virol 154(9): 1517-1522, 2009
  5. Watanabe T, Tsuda M, Tanaka S, Ohba Y, Kawaguchi H, Majima T, Sawa H, Minami A: The adaptor protein Crk induces Src-dependent activation of p38 MAPK in regulation of synovial sarcoma cell proliferation. Mol Cancer Res 7(9): 1582-1592, 2009
  6. Hasebe R, Sasaki M, Sawa H, Wada R, Umemura T, Kimura T: Infectious entry of equine herpesvirus-1 into host cells through different endocytic pathways. Virology 393(2): 198-209, 2009
  7. Takahashi H, Ohtaki N, Maeda-Sato M, Tanaka M, Tanaka K, Sawa H, Ishikawa T, Takamizawa A, Takasaki T, Hasegawa H, Sata T, Hall WW, Kurata T, Kojima A: Effects of the number of amino acid residues in the signal segment upstream or downstream of the NS2B-3 cleavage site on production and secretion of prM/M-E virus-like particles of West Nile virus. Microbes Infect 11(13): 1019-1028, 2009
  8. Kitagawa Y, Maeda-Sato M, Tanaka K, Tobiume M, Sawa H, Hasegawa H, Kojima A, Hall WW, Kurata T, Sata T, Takahashi H: Covalent bonded Gag multimers in Human Immunodeficiency virus type-1 particles. Microbiol Immunol 53(11): 609-620, 2009
  9. Niikura K, Nagakawa K, Ohtake N, Suzuki T, Matsuo Y, Sawa H, Ijiro K: Gold nanoparticle arrangement on viral particles through carbohydrate recognition: A non-cross|inking approach to optical virus detection. Bioconjug Chem 20(10): 1848-1852, 2009

著書

  1. Kasamatsu H, Nakanishi A, Liddington RC, Sawa H: Structural and Functional Studies of Polyomavirus Late Gene Products. In Yoshida K (ed) Molecular Biology of Tumor Virus Gene Products. Research Signpost, Kerala, India 2009, 109-168
  2. 鈴木 忠樹、大場 靖子、澤 洋文：プリオン病と遅発性ウイルス感染症：III 進行性多巣性白質脳症 （PML）、3. ウイルス検索と発症機序 303-309、2010 金原出版、東京、（厚生労働科学研究費補助金難治性疾患克服研究事業、プリオン病及び遅発性ウイルス感染症に関する調査研究班 編集）

2008

  1. Orba Y, Sunden Y, Suzuki T, Nagashima K, Kimura T, Tanaka S, Sawa H*: Pharmacological cdk inhibitor R-Roscovitine suppresses JC virus proliferation. Virology 370: 173-183, 2008 (* corresponding author)
  2. Hayashi Y, Kimura A, Kato S, Koumura A, Sakurai T, Tanaka Y, Hozumi I, Sunden Y, Orba Y, Sawa H, Takahashi H, Inuzuka T: Progressive multifocal leukoencephalopathy and CD4+ T-lymphocytopenia in a patient with Sjogren syndrome. J Neurol Sci 268: (1-2):195-198, 2008
  3. Nakae J, Cao Y, Oki M, Orba Y, Sawa H, Kiyonari H, Iskandar K, Lombes M, Hayashi Y: Forkhead transcription factor FoxO1 in adipose tissues regulates energy storage and expenditure. Diabetes 57:563-576, 2008
  4. Ohnishi N, Yuasa H, Tanaka S, Sawa H, Miura M, Matsui A, Higashi H, Musashi M, Iwabuchi K, Suzuki M, Yamada G, Azuma T, Hatakeyama M: Transgenic expression of Helicobacter pylori CagA induces gastrointestinal and hematopoietic neoplasms in mouse. Proc Natl Acad Sci USA 105:1003-1008, 2008
  5. Ohtake N, Niikura K, Suzuki T, Nagakawa K, Sawa H, Kuniharu I: Enhanced Cellular Uptake of Virus-Like Particles through Immobilization on a Sialic Acid-Displaying Solid Surface. Bioconjugate Chem 19:507-515, 2008
  6. Matoba T, Orba Y, Suzuki T, Makino Y, Shichinohe H, Kuroda S, Ochiya T, Itoh H, Tanaka S, Nagashima K, Sawa H*: An siRNA against JC virus (JCV) agnoprotein inhibits JCV infection in JCV-producing cells inoculated in nude mice. Neuropathology 28: 286-294, 2008 (* corresponding author)
  7. Hirano M, Rakwal R, Shibato J, Sawa H, Nagashima K, Ogawa Y, Yoshida Y, Iwahashi H, Niki E, Masuo Y: Proteomics- and transcriptomics-based screening of differentially expressed proteins and genes in brain of Wig rat: A model for attention deficit hyperactivity disorder (ADHD) research. J Proteome Res 7(6):2471-2489, 2008

2007

  1. Orba Y, Sunden Y, Suzuki T, Nagashima K, Kimura T, Tanaka S, Sawa H*: Pharmacological cdk inhibitor R-Roscovitine suppresses JC virus proliferation. Virology 370: 173-183, 2008 (* corresponding author)
  2. Ishii A, Matsuo A, Sawa H, Tsujita T, Shida K, Matsumoto M, Seya T: Lamprey TLRs with Properties Distinct from Those of the Variable Lymphocyte Receptors. J Immunol 178: 397-406, 2007
  3. Sunden Y, Semba S, Suzuki T, Okada Y, Orba Y, Nagashima K, Umemura T, Sawa H*: Identification of DDX1 as a JC virus (JCV) transcriptional control region-binding protein. Microbiol Immunol 51: 327-337, 2007 (* corresponding author)
  4. Sunden Y, Semba S, Suzuki T, Okada Y, Orba Y, Nagashima K, Umemura T, Sawa H*: DDX1 promotes proliferation of JC virus (JCV) through transactivation of the JCV promoter. Microbiol Immunol 51: 339-347, 2007 (* corresponding author)
  5. Ichinohe T, Nagata N, Strong P, Tamura SI, Takahashi H, Ninomiya A, Imai M, Odagiri T, Tashiro M, Sawa H, Chiba J, Kurata T, Sata T, Hasegawa H: Prophylactic effects of chitin microparticles on highly pathogenic H5N1 influenza virus. J Med Virol 79: 811-819, 2007
  6. Tsuji T, Sheehy N, Gautier VW, Hayakawa H, Sawa H, Hall WW: The nuclear import of the human T lymphotropic virus type I (HTLV-1) Tax protein is carrier and energy independent. J Biol Chem 282: 13875-13883, 2007
  7. Takaya A, Kamio T, Masuda M, Mochizuki N, Sawa H, Sato M, Nagashima K, Mizutani A, Matsuno A, Kiyokawa E, Matsuda M: R-Ras Regulates Exocytosis by Rgl2/Rlf-mediated Activation of RalA on Endosomes. Mol Biol Cell 18: 1850-1860, 2007
  8. Nakaoka Y,Nishida K, Narimatsu M,Kamiya A,TMinami T, Sawa H, Okawa K,Fujio Y,Koyama T, Maeda M, Sone M, Yamasaki S, Arai Y, Koh GY, Kodama T, Hirota H, Otsu K, Hirano T, Mochizuki N: Gab family proteins are essential for postnatal maintenance of cardiac function via neuregulin-1/ErbB signaling. J Clin Invest 117:1771-1781, 2007
  9. Ichinohe T, Tamura SI, Kawaguchi A, Ninomiya A, Imai M, Itamura S, Odagiri T, Tashiro M, Takahashi H, Sawa H, Chiba J, Kurata T, Sata T, Hasegawa H: Cross-protection against H5N1 influenza virus infection afforded by intranasal administration of seasonal trivalent inactivated influenza vaccine. J Infec Dis 196:1313-1320, 2007
  10. Masuo Y, Ishido M, Morita M, Sawa H, Nagashima K, Niki E: Behavioural characteristics and gene expression in the hyperactive wiggling (Wig) rat. Eur J Neurosci 25:3659-3666, 2007
  11. Ichinohe T, Kawaguchi A, Tamura SI, Takahashi H, Sawa H, Ninomiya A, Imai M, Itamura S, Odagiri T, Tashiro M, Chiba J, Kurata T, Sata T, Hasegawa H: Intranasal immunization with H5N1 vaccine plus Poly I:Poly C12U, a Toll-like receptor agonist, protects mice against homologous and heterologous virus challenge. Microbes Infect 9:1333-40, 2007
  12. Fujita T, Maturana AD, Ikuta J, Hamada J, Walchli S, Suzuki T, Sawa H, Wooten MW, Okajima T, Tatematsu K, Tanizawa K, Kuroda S: Axonal guidance protein FEZ1 associates with tubulin and kinesin motor protein to transport mitochondria in neurites of NGF-stimulated PC12 cells. Biochem Biophys Res Commun 361: 605-610, 2007
  13. Tabu K, Ohba Y, Suzuki T, Makino Y, Kimura T, Ohnishi A, Sakai M, Watanabe T, Tanaka S, Sawa H*: OLIG2 inhibits the motility of a human glial tumor cell line by activating RhoA. Mol Cancer Res 5:1099-109, 2007 (* corresponding author)

著書

  1. 澤 洋文、鈴木 忠樹、大場 靖子、寸田 祐嗣、長嶋 和郎：JCウイルスの最近の基礎的知見。BRAIN and NERVE 59: 101-108, 2007
  2. 鈴木 忠樹、長嶋 和郎、澤 洋文：進行性多巣性白質脳症 （PML）：原因ウイルスと発病機構。 日本臨床 65: 1495-1500, 2007
  3. 今村 栄次、山下 拓史、福原 敏行、澤 洋文、長嶋 和郎、桑原 正雄、時信 弘：高活性レトロウイルス療法により免疫再構築症候群をきたしたAIDSにともなう進行性多巣性白質脳症の1剖検例。臨床神経学47: 650-656, 2007

2006

  1. Takahashi H, Maeda M, Sawa H, Hasegawa H, Moriyama M, Sata T, Hall WW, Kurata T: Dicer and positive charge of proteins decrease the stability of RNA containing the AU-rich element of GM-CSF. Biochem Biophys Res Commun 340:807-814, 2006
  2. Sunden Y, Suzuki T, Orba Y, Umemura T, Asamoto M, Nagashima K, Tanaka S, Sawa H*. Characterization and application of polyclonal antibodies that specifically recognize JC virus large T antigen. Acta Neuropathol 111: 379-387, 2006 (*corresponding author)
  3. Makino Y, Tsuda, M Ichihara S, Watanabe T, Sakai M, Sawa H, Nagashima K, Hatakeyama S, Tanaka S. Elmo1 inhibits ubiquitylation of Dock180. J Cell Sci 119: 923-932, 2006
  4. Hasegawa H*, Sawa H*, Lewis MJ, Orba Y, Sherhy N, Yamamoto Y, Ichinohe T, Tsunetsugu-Yokota Y, Katano H, Takahashi H, Matsuda J, Sata T, Kurata T, Nagashima, K, Hall, WW. Development of Thymus-Derived T-cell Leukemia/Lymphoma in Mice Transgenic for the Tax gene of Human T-Lymphotropic Virus Type-I (HTLV-I). Nat Med 12: 466-472, 2006 (*These authors contributed equally to this work.)
  5. Linghu H, Tsuda M, Makino Y, Sakai M, Watanabe T, Ichihara S, Sawa H, Nagashima K, Mochizuki N, Tanaka S: Involvment of adaptor protein Crk in malignant feature of human ovarian cancer cell line MCAS. Oncogene 25: 3547-3556, 2006
  6. Tabu K, Ohnishi A, Sunden Y, Suzuki T, Tsuda M, Tanaka S, Sakai T, Nagashima K, Sawa H*: A novel function of OLIG2 to suppress human glial tumor cell growth via p27Kip1 transactivation. J Cell Sci 119:1433-41, 2006 (* corresponding author)
  7. Ichinohe T, Watanabe I, Tao E, Ito S, Kawaguchi A, Tamura SI, Takahashi H, Sawa H, Moriyama M, Chiba J, Komase K, Suzuki Y, Kurata T, Sata T, Hasegawa H: Protection against influenza virus infection by intranasal vaccine with surf clam microparticles (SMP) as an adjuvant. J Med Virol 78: 954-963, 2006
  8. Watanabe T, Tsuda M, Makino Y, Ichihara S, Sawa H, Minami A, Mochizuki N, Nagashima K, Tanaka S: Adaptor molecule crk is required for sustained phosphorylation of grb2-associated binder 1 and hepatocyte growth factor-induced cell motility of human synovial sarcoma cell lines. Mol Cancer Res 4: 499-510, 2006
  9. Maeda M, Sawa H, Tobiume M, Tokunaga K, Hasegawa H, Ichinohe T, Sata T, Moriyama M, Hall WW, Kurata T, Takahashi T: Tristetraprolin inhibits HIV-1 production by binding to genomic RNA. Microbes Infect 8: 2647-2656, 2006
  10. Ozaki YA, Itamura S, Ichinohe T, Strong P, Tamura S, Takahashi H, Sawa H, Moriyama M, Tashiro M, Sata T, Kurata T, Hasegawa H: Intranasal administration of adjuvant-combined recombinant influenza virus HA vaccine protects mice from the lethal H5N1 virus infection. Microbes Infect 8: 2706-2714, 2006
  11. Hasebe, R., Kimura, T., Nakamura, K., Ochiai, K. Okazaki, K., Wada, R. and Umemura, T. Differential susceptibility of equine and mouse brain microvascular endothelial cells to equine herpesvirus 1 infection. Arch. Virol. 151:775-86, 2006

2005

  1. Hasegawa H, Ichinohe T, Strong P, Watanabe I, Ito S, Tamura S-i, Takahashi H, Sawa H, Chiba J, Kurata T, Sata T: Protection against influenza virus infection by intranasal administration of HA vaccine with chitin microparticles as an adjuvant. J Med Virol 75: 130-136, 2005
  2. Henmi C, Sawa H*, Iwata H, Orba Y, Tanaka S, Nagashima K: Isolation of a monoclonal antibody recognizing a cell-surface molecule as a receptor for JC virus. Biochem Biophys Res Commun 327: 242-251, 2005 (* corresponding author)
  3. Ichinohe T, Watanabe I, Ito S, Moriyama M, Tamura S, Takahashi H, Sawa H, Chiba J, Kurata T, Sata T, Hasegawa H: Synthetic double-stranded RNA [poly (I:C)] combined with mucosal vaccine protects against influenza virus infection. J Virol 79: 2910-2919, 2005
  4. Khalili K, White MK, Sawa H, Nagashima K, Safak M: The agnoprotein of polyomaviruses: A multifunctional auxiliary protein. J Cell Physiol 204:1-7, 2005
  5. Sawa H, Nagashima T, Nagashima K, Shinohara T, Chuma T, Mano Y, Tachi N, Hall WW. Clinicopathological and virological analyses of familial HTLV-I associated polyneuropathy. J Neurovirol 11: 199-207, 2005
  6. Okada Y, Suzuki T, Sunden Y, Orba Y, Kose S, Imamoto N, Takahashi H, Tanaka S, Hall WW, Nagashima K, Sawa H*: Dissociation of heterochromatin protein 1 from lamin B receptor induced by human polyomavirus agnoprotein: role in nuclear egress of viral particles. EMBO Rep 6: 452-457, 2005 (* corresponding author)
  7. Suzuki T, Okada Y, Semba S, Orba Y, Yamanouchi S, Endo S, Tanaka S, Fujita T, Kuroda S, Nagashima K, Sawa H*: Identification of FEZ1 as a protein that interacts with JC virus agnoprotein and microtubules: role of agnoprotein-induced dissociation of FEZ1 from microtubules in viral propagation. J Biol Chem 280, 24948-24956, 2005 (* corresponding author).
  8. Akazawa S, Igarashi M, Sawa H, Tamashiro H: Strategic approach to information security and assurance in health research. Environ Health Prev Med 10: 282-285, 2005
  9. Tsuda M, Watanabe T, Seki T, Kimura T, Sawa H, Minami A, Akagi T, Isobe KI, Nagashima K, Tanaka S: Induction of p21(WAF1/CIP1) by human synovial sarcoma-associated chimeric oncoprotein SYT-SSX1. Oncogene. 24: 7984-7990, 2005
  10. Tanaka S, Nagashima K, Sawa H: The impact of molecular apathology in the diagnosis and prognosis of brain tumor. Brain tumor Pathol. 22: Suppl 2: 37-40, 2005
  11. Hatai, H., Ochiai, K., Tomioka, Y., Toyoda, T., Hayashi, K., Anada, M., Kato, M., Toda, A., Ohashi, K., Ono, E., Kimura, T. and Umemura, T. Nested polymerase chain reaction for detection of the avian leukosis virus causing so-called fowl glioma. Avian. Pathol. 34:473-479, 2005
  12. Matsuda, K., Shibata, T., Sakoda, Y., Kida, H., Kimura, T., Ochiai, K., Umemura, T. In vitro demonstration of neural transmission of avian influenza A virus. J. Gen. Virol. 86:1131-1139, 2005.
  13. Toyoda, T., Ochiai, K., Ohashi, K., Tomioka, Y., Kimura, T. and Umemura, T. Multiple perineuriomas in chicken (Gallus gallus domesticus). Vet. Pathol. 42:176-83, 2005.
  14. Sawa H, Komagome R: The JC virus-like particle overlay assay. In Lieberman PM (ed) Methods in Molecular Biology. Humana Press, Totowa, NJ 2005;292: 175-186

2004年以前の業績